Я сделал update со ссылкой, где про это исследование говорится: "The short version is the observation that subjects were recruited for this study by ads touting a "novel mind-body management study of IBS [irritable bowel syndrome], which introduced selection bias for people prone to be interested in "mind-body" interactions. Moreover, while it is true that Kaptchuk and his team told subjects that they would be receiving placebos, but they also told subjects that the sugar pills used "have been shown in rigorous clinical testing to produce significant mind-body self-healing processes," which is, to put it kindly, an exaggeration. Add to all this the way outcomes were measured were custom-designed to exaggerate. The no-treatment arm demonstrated an IBS Global Improvement Score of 4 (no change) compared to the Open Placebo arm, which averaged 5 (slightly improved). This is highly unlikely to be clinically significant. Despite all these problems, this study was widely touted as somehow being slam-dunk evidence that placebo effects can be invoked without deception when it is anything but. "
То есть механизм как и в других плацебо - пациентов уверили, что "должно сработать".
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timeasmymeasure
no subject
Date: 2012-01-04 03:40 pm (UTC)"The short version is the observation that subjects were recruited for this study by ads touting a "novel mind-body management study of IBS [irritable bowel syndrome], which introduced selection bias for people prone to be interested in "mind-body" interactions. Moreover, while it is true that Kaptchuk and his team told subjects that they would be receiving placebos, but they also told subjects that the sugar pills used "have been shown in rigorous clinical testing to produce significant mind-body self-healing processes," which is, to put it kindly, an exaggeration. Add to all this the way outcomes were measured were custom-designed to exaggerate. The no-treatment arm demonstrated an IBS Global Improvement Score of 4 (no change) compared to the Open Placebo arm, which averaged 5 (slightly improved). This is highly unlikely to be clinically significant. Despite all these problems, this study was widely touted as somehow being slam-dunk evidence that placebo effects can be invoked without deception when it is anything but. "
То есть механизм как и в других плацебо - пациентов уверили, что "должно сработать".